A to Z of drugs and trials
Heard about a drug or a trial? Find it here.
Every trial in people on this site, 129 in all, by name. The search also covers discoveries, genes, the glossary and the main pages.
A
- AAV-AADC · a gene therapy that helps the brain turn levodopa into dopamine
- AAV2-GAD · a gene therapy that calms an overactive movement area of the brain
- ADAGIO · rasagiline, a pill
- AKST4290 (TEAL) · a pill that blocks an immune receptor called CCR3
- ALN-SNCA · a drug that makes cells produce less of the protein
- AMBITIOUS · ambroxol, a cough medicine, at about ten times the cough dose
- Ambroxol, early studies · ambroxol, a cough medicine
- Anle138b · a pill to stop clumps forming
- ASPIRO · dopamine cell precursors made from each person's own skin cells
- ASPro-PD · ambroxol, a cough medicine
- Australian Parkinson's Mission APM001
- AZA-PD · azathioprine, a drug that dampens the immune system
B
- BEACON · BIIB122, in people with an LRRK2 gene change
- Bemdaneprocel Phase 1 · dopamine nerve cells grown from embryonic stem cells
- BHV-8000 · a pill that calms the immune system
- BIA 28-6156 · BIA 28-6156, a pill meant to raise the enzyme GCase
- Brigham own-cell trial · dopamine nerve cells made from each person's own blood cells
- Buntanetap · a pill
C
- CALM-PD β-CIT and REAL-PET
- CAP-003 · a gene therapy for GBA gene Parkinson's, given by vein
- CDNF · a growth-factor protein infused into the brain
- CERE-120 · a gene therapy that makes the brain produce neurturin, a growth factor
- Chinese iPS trials · dopamine cell precursors made from stem cells
- CNM-Au8 · CNM-Au8, a drink of gold nanocrystals, made by a company
- Coenzyme Q10, Phase 2 · coenzyme Q10, a supplement
- Coenzyme Q10, QE3 · coenzyme Q10, a supplement
- Creatine · creatine, a supplement
D
- DAPA-PD · dapansutrile, a tablet that blocks NLRP3
- DATATOP · deprenyl, a pill, and vitamin E
- DNL151 safety studies · BIIB122 (then called DNL151), a tablet that blocks LRRK2
- DNL201 · an early LRRK2 blocker
E
- EARLYSTIM early DBS
- EFFACE-PD · a faecal transplant, given once by colonoscopy
- ELLDOPA: levodopa and progression
- ENT-01 (KARMET) · squalamine, a pill aimed at gut nerves
- EPI-589 · EPI-589, a pill meant to protect cells from oxidative stress
- Exenatide pilot · exenatide, a diabetes drug
- Exenatide-PD3 · exenatide, a diabetes drug
- Exercise (SPARX and SPARX3) · hard treadmill exercise
- EXIST · exidavnemab, an antibody drug
- exPDite-2 · bemdaneprocel, dopamine nerve cells grown from embryonic stem cells
F
- FAIRPARK-II · deferiprone, a pill that removes iron
- Finnish faecal transplant trial · a faecal transplant, given once by colonoscopy
- First fetal grafts · grafts of dopamine-making cells from donated fetal tissue
- First own-cell graft · nerve cells made from a patient's own skin cells
- Focused ultrasound · sound waves that briefly open the barrier between blood and brain
- Fosgonimeton · an injected drug meant to boost a growth-factor pathway
- Freed fetal grafts · grafts of dopamine-making cells from donated fetal tissue
G
- GBA gene therapy · gene therapy: one injection of a working GBA gene near the brain
- GDNF infusions · a growth-factor protein pumped into the brain
- GM1 ganglioside · a fat-like molecule found in nerve cell membranes
- GRF6021 · an infusion made from donated blood plasma
- GT-02287 · GT-02287, a pill meant to restore the enzyme GCase
- GUT-PARFECT · a faecal transplant, given through a tube into the bowel
H
- HCQ-PD · hydroxychloroquine, an arthritis and malaria drug
- Hydrogen water · water with hydrogen gas dissolved in it
I
K
- Kyoto iPS trial · dopamine cell precursors made from donor stem cells (iPS cells)
L
- LEAP · levodopa, the main Parkinson's medicine
- LixiPark · lixisenatide, a diabetes drug
- Low-dose lithium · a small study in Buffalo, USA
- LRRK2 antisense drug · BIIB094, an injection into the spinal fluid that makes cells produce less LRRK2
- LUMA · BIIB122, an LRRK2 drug
- LY3962681 · a drug that makes cells produce less of the protein
M
- Mass General own-cell trial · dopamine cell precursors made from each person's own skin cells
- MitoQ · mitoquinone, a pill that carries an antioxidant into mitochondria
- MOST-ABLE (Osaka) · semaglutide, a diabetes drug, as a daily tablet
- MTX325 and ABBV-1088 · pills meant to restart the clearing of damaged mitochondria
N
- N-DOSE · nicotinamide riboside, a form of vitamin B3, at three doses
- NAC · N-acetylcysteine (NAC), a supplement that helps the body make glutathione
- NADPARK · nicotinamide riboside, a form of vitamin B3
- Nasal glutathione · glutathione, the brain's own antioxidant, as a nose spray
- NET-PD futility screens FS-1 and FS-2
- NEULARK · NEU-411, a second LRRK2 blocker
- Nilotinib · a leukaemia drug
- NLY01 · a long-acting diabetes-type drug aimed at brain immune cells
- NOPARK · nicotinamide riboside, a form of vitamin B3
- NOSE-PD · a nasal spray of insulin plus glutathione
- NouvNeu001 · dopamine cell precursors made from donor stem cells with chemicals
- NR-SAFE · nicotinamide riboside, at three times the earlier dose
- Nusinersen · an antisense drug injected into spinal fluid
O
- Olanow fetal grafts · grafts of dopamine-making cells from donated fetal tissue
- ORCHESTRA · minzasolmin, a pill
P
- PARAISO · prasinezumab, an antibody drug
- PASADENA and PADOVA · prasinezumab, an antibody drug
- PD STAT · simvastatin, a cholesterol drug
- PD01A vaccine · a vaccine against the protein
- PDGF-BB · a growth-factor protein given into the brain's fluid spaces
- Pioglitazone (FS-ZONE) · pioglitazone, a diabetes pill
- PRECEPT · CEP-1347, a pill meant to stop cells dying
- PreCoDe · prasinezumab, an antibody drug
- PRISMS · adalimumab, an antibody drug that calms inflammation
- ProSavin · a gene therapy giving brain cells three dopamine-making genes
- PROSEEK · vodobatinib, a leukaemia-type pill
- PROUD · pramipexole, a standard Parkinson's medicine
- PT320 · a slow-release form of exenatide
R
- Radotinib · a leukaemia drug
- REGENERATE-PD · AB-1005, a gene therapy that makes the brain produce GDNF
- REPLACE (Kenai) · ready-made dopamine cell precursors from donor stem cells
- Risvodetinib · a pill that blocks c-Abl, an enzyme
- ROCK-PD · fasudil, a drug used in Japan for other illnesses
S
- Sargramostim · sargramostim, a white blood cell growth drug
- Semaglutide trials (Oslo, Osaka) · semaglutide, a diabetes drug
- Soroka faecal transplant pilot · a faecal transplant, which puts donor gut bacteria into the bowel
- SPARK · cinpanemab, an antibody drug
- Spheramine · retinal cells that make levodopa, placed in the brain
- STEADY-PD III · isradipine, a blood-pressure pill
- STEM-PD · dopamine cell precursors made from embryonic stem cells
- Stockholm exenatide trial · exenatide, a diabetes drug
- SURE-PD3 · inosine, a pill that raises urate, a natural antioxidant in blood
- Synuclein-lowering drugs (overview)
T
- TARBELA-PD · RO7568282, a capsule that blocks NLRP3
- TB006 · an antibody drug aimed at inflammation
- TCH346 · a pill meant to stop cells dying
- TEMPO · rasagiline, a pill
- Terazosin pilot · terazosin, a prostate drug
- TJ0113 · TJ0113, a pill from a Chinese company
- TRANSEURO · grafts of dopamine-making cells from donated fetal tissue
U
- UB-312 vaccine · a vaccine against the protein
- UC San Diego trial · dopamine cell precursors made from donor stem cells, the same cells as Kyoto
- UDCA · ursodeoxycholic acid (UDCA), an old liver drug
V
- VacSYn · ACI-7104, a vaccine
- Vanderbilt early-DBS pilot
- Venglustat · venglustat, a pill that cuts the raw material for the enzyme GCase
- VENT-02 · an NLRP3 blocker, a pill
- VGN-R08b · a gene therapy giving a working GBA1 gene, injected into the brain's fluid spaces
- VTX3232 · an NLRP3 blocker, a pill that calms inflammation
- VY-AADC · a gene therapy that helps the brain make dopamine